According to the report, 303 men participated in this research. It is said to be the first successful contraceptive injection for men that can prevent a partner’s pregnancy for a long time.
What does the research say?
According to the results of an open-label and non-randomized phase-III study published in the International Open Access Journal Andrology, 303 healthy, sexually active and married men, aged between 25 and 40 years, were given family Participants were selected from the planning clinics. participated in this research. These people were given 60 mg of risag.
The research found that Risug was 99.02 percent successful in preventing pregnancy, that too without any side effects. Risg achieved 97.3% azoospermia, which is a medical term indicating that no sperm are present in the ejaculated semen. The research participants’ wives were also monitored and found to be unaffected.
Dr. RS Sharma, who is retiring from ICMR in 2022 and has devoted more than 20 years to writing and authoring the study, says, ‘Ultimately, through this research, we have been able to address two main concerns about RIsag. . The first is how long the contraceptive will be effective and the second is how safe it is for people taking the contraceptive.
A study conducted by the Ministry of Health found that some men experienced side effects such as fever, swelling and urinary tract infections after the Risag injection, but they recovered within a few weeks to three months.
Dr. Risag from IIT Kharagpur. Developed by Sujoy Kumar Guha. Dr. Sujoy published the first scientific paper on RESG in the journal Contraception in 1979. It took almost 40 years to complete the phase-3 trial of this contraceptive. Hospital-based research was conducted at five centers in Jaipur, New Delhi, Udhampur, Kharagpur and Ludhiana.
What is Resig and how does it work?
Risg is based on injecting a polymeric agent called styrene maleic anhydride (SMA) into the spermatic duct via di-methyl sulfoxide (DMSO). Sperm cells reach the secretory organs from the testicles only through the vas deferens.
Risag is injected into the two sperm ducts (vas deferens) that carry sperm from the testicles to the reproductive organs. First, anesthesia is administered where the testicle is to be injected. Risag is then injected into the first and then the second spermatic cord respectively.
Once injected, the polymer adheres to the walls of the vas deferens. When the polymer sperm comes into contact with negatively charged sperm, it breaks off their tails, rendering them unable to fertilize.
Revolutionary change for women
Until now men only used condoms for birth control, but men had no way to prevent pregnancy after intercourse. Contraceptive pills that women currently take to prevent pregnancy have adverse effects on their health. In fact, it disturbs the hormonal balance in women. Scientists believe that the introduction of male birth control will have a positive impact on women’s health and lives because the entire responsibility for contraception will not rest on women.